Numeric Differences Between Two Different Dataframes In Python

I would like to find the numeric difference between two or more columns of two different dataframe.

The following

would be the starting table.
This one Table (Table 2)

contains the single values that I need to subtract to Table 1.

I would like to get a third table where I get the numeric differences between each row of Table 1 and the single row from Table 2. Any help?

Try

df.subtract(df2.values)

with df being your starting table and df2 being Table 2.